Take care mate
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Take care mate
Cheers, have no symptoms so I'm probably fine (and was not in that close contact). On the bright side: the corona app works, I got a notification (was already notified by my friend before, but still!), works nice and gave clear information what to do next (which is stay home, have someone do your groceries, and if you have any symptoms arrange a test).
University is so fucked.
I have a nephew in his first year of uni, who is in halls of residence/shared accommodation.
5 out of the 25 students in his hall have now tested positive.
500 ostensibly smart people sign dangerous and extremely stupid letter:
Twitter Link
My ex, his girlfriend, and 18 family members tested positive after a family funeral in Alabama. They carried the virus to at least 5 states before they tested positive, so they've undoubtedly spread it to others. (I'm sooo glad my sons didn't go because they worried it might be a super-spreader event!
Most had mild/moderate symptoms like the flu, but the gf has neurological complications (loss of smell and taste, plus foggy 'covid brain')....but one cousin is in a dedicated covid ICU trying to avoid the ventilator. :(
10 days after testing positive, the ex held an Election Night Wine Tasting Party with 6 others. Because he felt ok and "probably" isn't contagious (no, he hasn't been re-tested) and the group was small. No one declined. Smart people doing stupid stuff is just so confounding. :bulb:
Sorry to hear this, but glad you and your sons weren't exposed. Social pressure to gamble with your and other people's lives is absurdly high r n.
Wow, this is great news if confirmed. 50% would be good news for a vaccine, 90% is incredible.
Twitter Link
It's probably a silly question but should we worry over the long-termeffects from a covid19 vaccine?
(I'm not even sure what those would be; most likely it's a good thing to have)
I'm bloated, when it comes to vaccine I feel like here you got a 'market' were you could potentially inject anything.
So it's like improving the body by collecting different vaccines, is there ever a risk?
It's the pre-cyborg area.
Yes, no one knows what those consequences will be. I assume most side-effects would be visible at an earlier stage though.
I'm not really sure what kind of side effects are geberally associated with vaccines - could be long term as well, I imagine.
Also some good news: over here the number of new cases are dropping for more than a week now, and number of cases in the hospital seems to be stable / dropping slightly. Side note is that also fewer people got tested, but perhaps also because fewer people needed to. Numbers are still quite high, but I'm cautiously optimistic :) And tomorrow is already the last day of my self quarantine, did not get any symptoms. Looking forward to talking a walk outside again - today the weather was gorgeous but stayed inside :(
This is going to be a very difficult debate here in Sweden, where hundreds of people developed narcolepsy as a result of vaccination with Pandemrix, most of whom were diagnosed characteristically late. On the whole, vaccines are safe—and less dangerous than the diseases they protect against. Serious adverse effects do occur, but they're very rare. I have diagnosed four patients with narcolepsy that appears to have manifested after Pandemrix vaccination, but that's a special situation; my clinic occasionally has patients who've developed autoimmune neurological conditions shortly after vaccination (most commonly flu shot), but, even if you assume a causal relationship, those cases are exceedingly rare—more rare than similar conditions arising after a viral infection such as the flu, for example. There is no compelling evidence to support any of the common (in antivaxx circles) misconceptions about adjuvants, preservatives, accumulation, etc. We know nothing useful about long-term effects or adverse effects of a coronavirus vaccine—it's been barely half a year, after all. Conversely, we're learning more and more about otherwise healthy young-ish people suffering from bothersome covid-associated symptoms over six months after they first had—and ostensibly recovered from—covid. I think this constellation of "long covid" symptoms and the like are likely to be more prevalent and more bothersome than side-effects of a vaccine—at the group level at least.
Exactly, I think it's a foregone conclusion that young people here at least will not be lining up to get vaccinated. But people with elevated risk make up close to half the population, and I think uptake will be quite low in that population as well. Most likely best case scenario here is that institutionalized and/or frail elderly and others who are more zealously immunized—due to disease or certain treatments—will be vaccinated. Unless something unforeseen happens like vaccination requirements for travel.
Interesting company BioNTech. I've actually heard a lot of coverage about them in the last few days, nice anecdote that they were working on their wedding day (makes me think of Sheldon and Amy in Big Bang Theory). They've done a very, very good job.
Confidence seems high that their one working is a good indicator the Oxford/AZ one should work too as they both target the same protein. Very different designs though with the BioNTech one requiring -80C temperatures and the Oxford one doesn't so they may not work the same way.
Agreed that BioNTech should share the credit, but it's important to note that scaling up production of a new type of vaccine with a whole host of unknowns associated with it is not a trivial matter. Nor is running a largish clinical trial at breakneck speed. Pfizer deserves credit along with BioNTech.
This guy is so fucking dumb and so fucking weird:
Twitter Link
It's like listening to Lewk. What a ludicrous moron.
That's not very surprising. The main function of jails is to hold people before trial.
It's not surprising, but it's unjust.
Learn something every day, I thought they were interchangeable synonyms. I don't think there's a distinction in the UK, that seems to be a US thing.
They are. We have a jail here that is both a holding location, it's even surrounded by bail businesses, and it's a medium to high security direct supervision facility.
https://teamhcso.com/Section/708bcd1...ntion-Services
You have to be sentenced to more than a year in prison to get tranferred out of our local jail.
Early days from phase III testing of another vaccine, but looks to be at least as good as the Pfizer one, if not slightly more effective.Quote:
Originally Posted by BBC
... and a third one on the way also in phase III testing which is also looking very promising, UK developed by Oxford University and AstraZeneca.
I am really impressed with the time it's taken to develop these vaccines, and how successful they would appear to be. Incredible modern medicine brought to bear on such a critical problem.
~
Vaccines under development:
https://live.staticflickr.com/65535/...a1e6ec79_o.jpg
https://live.staticflickr.com/65535/...4c14b3e4_o.jpg
Early days, lots more to learn about duration of effect, more statistically significant results, and a full accounting for side effects. I'm cautiously optimistic but we should not jump to conclusions on the basis of very preliminary data. Also, you should not assume there is a substantial difference in efficacy between the two vaccines; I don't know the confidence interval in their current power, but I'd bet it's pretty big.
The big issue is stability with mRNA vaccines. Moderna has better stability data to date, but we're still talking cold chain shipping and storage, meaning it's going to be hard to deploy in rural developing areas. Pfizer's current stability data is pretty poor, though, so we're really only talking sophisticated healthcare settings in the rich world. Some of the follow-on efforts (e.g. adenoviruses and proteins and the like) may be more stable.
Good news? In theory it should be possible to make a lot of doses, very quickly. Oligonucleotide-based vaccines can potentially be deployed quickly.
The other consideration is dosing regimens. I think that even though they're running a bit behind, JNJ's effort may end up paying off in the end - they're pushing for a single dose formulation, and likely one with pretty decent temperature stability. The logistical headache of rolling out hundreds of millions of two-dose treatments, all spaced by 3-4 weeks, is challenging.
I agree, this vaccine development has been nothing short of phenomenal in both scope and speed. What's more impressive is that we've been kicking the tires on some novel vaccine designs for a while but haven't deployed them - but have now gotten multiple candidates on totally new vaccine types in Phase III trials.
I do want to caution, though, that because of the breakneck speed there are going to be setbacks, and some vaccines will end up being more effective than others, and deployment will be lumpy at best. But all things being equal the biotech/pharma world has really stepped up here.
Just leaving this here:
Twitter Link
One of the ten dumbest men in English politics.
Just leaving this here:
Twitter Link
One of the ten dumbest men in English politics.
He has been a complete moronic twerp during the whole pandemic. Total idiot.
https://edition.cnn.com/2020/11/17/u...ors/index.html
I remember way back in the day of this thread, a certain individual was posting numbers per American state. He stopped doing so.Quote:
Gov. Kristi Noem, a Republican in office since 2019, has adopted much of the language of President Donald Trump during the pandemic.
The results have been devastating health-wise. South Dakota has averaged more than 1,400 new coronavirus cases per day over the past week in a state with about 885,000 people. Adjusted for population, it's the second-highest number of new average cases in the country. The state's seven-day positivity rate is a stunning 58%, and more people are hospitalized per capita than in any other state, according to the Covid Tracking Project.
[...]
Gov. Doug Burgum, a businessman who was elected as a Republican in 2016, had resisted a mask mandate since the pandemic began.
But that stance became untenable in recent weeks as Covid-19 has run through the state. Per capita, North Dakota has the most new coronavirus cases and deaths over the past seven days of any US state, and is second in new hospitalizations only to South Dakota.
[...]
In the country's least populous state, Gov. Mark Gordon, a Republican who took office in 2019, did not issue stay-at-home orders in the spring and has not required people to wear masks.
Yet after months of advising residents to take "personal responsibility" to protect themselves, he admitted Friday that the strategy had failed. Wyoming has the fourth-highest number of daily new coronavirus cases per capita over the past seven days, along with sharply rising hospitalizations and deaths.
[...]
Gov. Kim Reynolds, a Republican who assumed office in 2017, has resisted mask mandates and shutdowns for months.
Last month, she attended a Trump rally without a mask, violating her own rules on gatherings. She has ignored increasingly dire warnings from the White House coronavirus task force to institute a mask mandate over the past few months.
Now, Iowa is behind only the Dakotas in its measure of new coronavirus cases when adjusted for population, and the state has the fourth-highest number of people hospitalized per capita. Its seven-day positivity rate is more than 50%, behind just South Dakota and Wyoming.
[...]
Gov. Pete Ricketts, a Republican businessman who has served as governor since 2015, went further than almost any other governor in his resistance to mask mandates.
In June, he told local government officials that they won't get federal coronavirus relief funding if they require individuals to wear face masks in government buildings. He said masks should be encouraged but not required, and put the enticement of CARES Act money behind that position.
Months later, and still with no mask mandate, the state has seen huge surges in coronavirus cases. Adjusted for population, Nebraska has the fifth-most new cases over the past week and the third-most people hospitalized.
I wonder why.
And if we go by countries - Belgium, UK, Spain and Italy in Europe all have higher per capita deaths than America. Hell Belgium's per capita deaths are *accelerating* compared to America.
Indeed, while the death per capita rate in the US was considerably higher than European countries while they were under lockdown through June, July, August, those European countries have had deaths skyrocket since they emerged from lockdown at the end of summer.
https://live.staticflickr.com/65535/...405b27dd_o.jpg
However, since those same European countries are now entering periods of further restriction and lockdown, the sharp rise in cases has tailed off and in most cases reversed.
Whereas the US, which is not implementing the same restrictions and lockdown measures at the moment, is seeing a steep increase in cases as below with no sign of tailing off.
The death rate will follow the flow of cases with the same delay as before, with a decrease in those European countries, but increasing in the US over the next few months.
https://live.staticflickr.com/65535/...fb151f13_o.jpg
Oh I'm sorry, did you miss these?
"Per capita, North Dakota has the most new coronavirus cases and deaths over the past seven days of any US state", "Wyoming has the fourth-highest number of daily new coronavirus cases per capita over the past seven days, along with sharply rising hospitalizations and deaths.", "Iowa is behind only the Dakotas in its measure of new coronavirus cases when adjusted for population, and the state has the fourth-highest number of people hospitalized per capita. Its seven-day positivity rate is more than 50%, behind just South Dakota and Wyoming.", "Adjusted for population, Nebraska has the fifth-most new cases over the past week and the third-most people hospitalized.".