Quote Originally Posted by LittleFuzzy View Post
Rand, have you considered what the effect it can have on the effectiveness of the 2nd dose, once it finally does get administered? Because we don't know that either but informed speculation and what little clinical data there is also tells us that the effect will be weaker. You may be ensuring that in the long-run, 100% of those vaccinated under your strategy might as well have been given a placebo.
Yes. The JCVI, MHRA and others have said they expect the effect of the booster to be STRONGER after a 12 week gap. Not weaker.

Both data from the AZN trial and a general understanding of how booster shots work and the historical body of evidence with booster shots in general leads them to have confidence in that.

What informed speculation or clinical data do you have that it will be weaker?