A: Why is this on the agenda? Why waste political capital on this? What's the effect other than pissing off moderate female voters?
B: One can support abortion without making it the centerpiece of most Republican campaigns. The pre-Reagan Republicans managed to do this just fine.
D: These issues explicitly target Muslims. The supporters of the measures know that, and the Muslims know that. Why give up on the Muslim vote just to pander to some lunatics (and these things are part of GOP platforms in at least several states)?
E: Yeah, the entire "war on religion/Christmas/Christians" that makes the headlines every year must be a figment of my imagination. As are the constant attempts to get the 10 commandments into courtrooms.
F: This is the kind of mentality that will lead the GOP to a path of destruction. You can cherry pick all the data you want. The Republican Party is incredibly hostile to immigration reform. The few Republicans who try to deal with the issue either get shouted down or ignored.
G: Yeah, it's not like Republicans regularly try to push the teaching of creationism/ID, or try to defund various sciences, or talk about conspiracies by the scientific community. It's telling that the Democratic get out the vote, fundraising, and political targeting methods are run almost entirely by trained statisticians, while the GOP is either unable or unwilling to do the same with its own election strategies.
H: The "stop giving foreign aid" line is mainly a Republican one. As is the obsession with how awful the UN is. On the flip side, any time a president talks to leaders of countries that are hostile to us, there are always Republican politicians waiting to attack him.
I:
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J: DeMint has actively campaigned against GOP incumbents who weren't "conservative enough". Even ignoring DeMint, the GOP has refused to take a stand against Tea Party extremists. You can't all pretend to be Tea Partyers and then rail against the base when it forces moderate Republicans from office.